Functional medicine is a personalized approach to healthcare that focuses on primary prevention and addressing the root causes of chronic diseases, rather than just treating symptoms. This science-based field is built upon the following principles:

  • Biochemical Individuality: Recognizing the unique metabolic variations that result from genetic and environmental factors, which influence each person’s health and response to treatments.
  • Patient-Centered Care: Prioritizing the individual patient rather than just the disease, echoing Sir William Osler’s belief that “It is more important to know what patient has the disease than to know what disease the patient has.”

Dynamic Balance of Internal and External Factors

The human body functions as an interconnected network, where physiological systems do not work in isolation, but are linked and influence each other. A growing body of research supports this view, highlighting how imbalances in one area can affect others. For instance, immune dysfunctions can contribute to cardiovascular disease, dietary imbalances can disrupt hormonal regulation, and environmental factors can trigger neurological disorders like Parkinson’s disease.

Health as Positive Vitality
Health should be viewed as a state of vitality and well-being, not just the absence of disease. Functional medicine aims to promote organ reserve, enhancing health span and supporting longevity.

Core Clinical Imbalances and Their Origins
Functional medicine examines the fundamental imbalances in the body that underlie disease. These imbalances arise as the body processes environmental inputs—such as diet, nutrients, exercise, trauma, and environmental exposures—through a unique set of genetic predispositions, beliefs, and attitudes. Essential physiological processes include cellular communication, bioenergetics (the conversion of food into energy), replication and repair, waste elimination, protection and defense, and circulation. When disruptions occur in these processes, they can lead to:

  • Hormonal and neurotransmitter imbalances
  • Oxidation-reduction imbalances and mitochondrial dysfunction (mitochondropathy)
  • Detoxification and biotransformation imbalances
  • Immune system imbalances
  • Inflammatory imbalances
  • Digestive, absorptive, and microbiological imbalances
  • Structural imbalances, from cellular function to the musculoskeletal system

These imbalances are often the precursor to the symptoms that lead to the diagnosis of disease. Addressing and restoring balance in both environmental factors and physiological processes is key to improving health, and it goes beyond simply treating symptoms.

Functional Medicine’s Approach to Chronic Disease
Functional medicine is dedicated to managing complex, chronic diseases by intervening at multiple levels to address these core imbalances. It aims to restore the body’s functionality and overall health by focusing on the root causes of disease, rather than just symptom management.

An Integrated and Evidence-Based Approach
Functional medicine is not a separate field but is grounded in scientific principles from a range of medical disciplines. It combines research to create detailed, clinically relevant models for understanding disease and improving clinical management. This approach emphasizes a teachable, integrated process that draws from multiple knowledge bases, focusing on functionality at many levels. It uses the patient’s personal story as a crucial tool to link diagnosis, symptoms, and clinical imbalances into a comprehensive strategy that improves environmental inputs and physiological health.

Transforming Primary Care
Functional medicine seeks to transform primary care practice by emphasizing a holistic and patient-centered approach. It addresses complex health issues by focusing on the underlying causes, aiming to restore health and functionality in a more personalized and effective manner.

Definition of Functional Medicine, The Institute for Functional Medicine